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Macrophage infiltration and alternative activation during wound healing promote MEK1-induced skin carcinogenesis

Macrophages are essential for the progression and maintenance of many cancers, but their role during the earliest stages of tumor formation is unclear. To test this, we used a previously described transgenic mouse model of wound-induced skin tumorigenesis, in which expression of constitutively activ...

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書誌詳細
出版年:Cancer Res
主要な著者: Weber, Christine, Telerman, Stephanie B., Reimer, Andreas S., Sequeira, Ines, Liakath-Ali, Kifayathullah, Arwert, Esther N., Watt, Fiona M.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4757739/
https://ncbi.nlm.nih.gov/pubmed/26754935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-3676
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