Effect of Anti-Sclerostin Therapy and Osteogenesis Imperfecta on Tissue-level Properties in Growing and Adult Mice While Controlling for Tissue Age

Bone composition and biomechanics at the tissue-level are important contributors to whole bone strength. Sclerostin antibody (Scl-Ab) is a candidate anabolic therapy for the treatment of osteoporosis that increases bone formation, bone mass, and bone strength in animal studies, but its effect on bon...

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Bibliographische Detailangaben
Veröffentlicht in:Bone
Hauptverfasser: Sinder, Benjamin P., Lloyd, William R., Salemi, Joseph D., Marini, Joan C., Caird, Michelle S., Morris, Michael D., Kozloff, Kenneth M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4757447/
https://ncbi.nlm.nih.gov/pubmed/26769006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2016.01.001
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