Increased mRNA Levels of Sphingosine Kinases and S1P Lyase and Reduced Levels of S1P Were Observed in Hepatocellular Carcinoma in Association with Poorer Differentiation and Earlier Recurrence

Although sphingosine 1-phosphate (S1P) has been reported to play an important role in cancer pathophysiology, little is known about S1P and hepatocellular carcinoma (HCC). To clarify the relationship between S1P and HCC, 77 patients with HCC who underwent surgical treatment were consecutively enroll...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Uranbileg, Baasanjav, Ikeda, Hitoshi, Kurano, Makoto, Enooku, Kenichiro, Sato, Masaya, Saigusa, Daisuke, Aoki, Junken, Ishizawa, Takeaki, Hasegawa, Kiyoshi, Kokudo, Norihiro, Yatomi, Yutaka
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4757388/
https://ncbi.nlm.nih.gov/pubmed/26886371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149462
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