Increased mRNA Levels of Sphingosine Kinases and S1P Lyase and Reduced Levels of S1P Were Observed in Hepatocellular Carcinoma in Association with Poorer Differentiation and Earlier Recurrence

Although sphingosine 1-phosphate (S1P) has been reported to play an important role in cancer pathophysiology, little is known about S1P and hepatocellular carcinoma (HCC). To clarify the relationship between S1P and HCC, 77 patients with HCC who underwent surgical treatment were consecutively enroll...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Uranbileg, Baasanjav, Ikeda, Hitoshi, Kurano, Makoto, Enooku, Kenichiro, Sato, Masaya, Saigusa, Daisuke, Aoki, Junken, Ishizawa, Takeaki, Hasegawa, Kiyoshi, Kokudo, Norihiro, Yatomi, Yutaka
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4757388/
https://ncbi.nlm.nih.gov/pubmed/26886371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149462
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