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The use of modified and non-natural nucleotides provide unique insights into pro-mutagenic replication catalyzed by polymerase eta
This report evaluates the pro-mutagenic behavior of 8-oxo-guanine (8-oxo-G) by quantifying the ability of high-fidelity and specialized DNA polymerases to incorporate natural and modified nucleotides opposite this lesion. Although high-fidelity DNA polymerases such as pol δ and the bacteriophage T4...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4756837/ https://ncbi.nlm.nih.gov/pubmed/26717984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1509 |
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