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Cell-of-Origin of Cancer versus Cancer Stem Cells: Assays and Interpretations

A tumor originates from a normal cell that has undergone tumorigenic transformation as a result of genetic mutations. This transformed cell is the cell-of-origin for the tumor. In contrast, an established clinical tumor is sustained by subpopulations of self-renewing cancer cells operationally calle...

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Détails bibliographiques
Publié dans:Cancer Res
Auteurs principaux: Rycaj, Kiera, Tang, Dean G
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4756645/
https://ncbi.nlm.nih.gov/pubmed/26292361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-0798
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