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Cancer stem cells and cell size: A causal link?
The majority of normal animal cells are 10–20 µm in diameter. Many signaling mechanisms, notably PI3K/Akt/mTOR, Myc, and Hippo pathways, tightly control and coordinate cell growth, cell size, cell division, and cell number during homeostasis. These regulatory mechanisms are frequently deregulated du...
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| Pubblicato in: | Semin Cancer Biol |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4651715/ https://ncbi.nlm.nih.gov/pubmed/26241348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2015.07.002 |
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