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Cancer Stem Cells: Constantly Evolving and Functionally Heterogeneous Therapeutic Targets

Elucidating the origin of and dynamic interrelationship between intratumoral cell subpopulations has clear clinical significance in helping understand the cellular basis of treatment response, therapeutic resistance, and tumor relapse. Cancer stem cells (CSC), together with clonal evolution driven b...

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Autori principali: Yang, Tao, Rycaj, Kiera, Liu, Zhong-Min, Tang, Dean G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4112560/
https://ncbi.nlm.nih.gov/pubmed/24713433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-0266
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