The role of HIF-1 in oncostatin M-dependent metabolic reprogramming of hepatic cells

BACKGROUND: Hypoxia and inflammation have been identified as hallmarks of cancer. A majority of hepatocellular carcinomas are preceded by hepatitis B- or C-related chronic infections suggesting that liver cancer development is promoted by an inflammatory microenvironment. The inflammatory cytokine o...

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Vydáno v:Cancer Metab
Hlavní autoři: Battello, Nadia, Zimmer, Andreas David, Goebel, Carole, Dong, Xiangyi, Behrmann, Iris, Haan, Claude, Hiller, Karsten, Wegner, Andre
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4756539/
https://ncbi.nlm.nih.gov/pubmed/26889381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40170-016-0141-0
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