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Deficiency of Circadian Clock Protein BMAL1 in Mice Results in a Low Bone Mass Phenotype

The circadian clock is an endogenous time keeping system that controls the physiology and behavior of many organisms. The transcription factor Brain and Muscle ARNT-like Protein 1 (BMAL1) is a component of the circadian clock and necessary for clock function. Bmal1(−/−) mice display accelerated agin...

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Publicat a:Bone
Autors principals: Samsa, William E., Vasanji, Amit, Midura, Ronald J., Kondratov, Roman V.
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755907/
https://ncbi.nlm.nih.gov/pubmed/26789548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2016.01.006
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