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Dimerization of glycoprotein Ibα is not sufficient to induce platelet clearance
BACKGROUND: The mechanism of platelet clearance is not clear. Many antibodies binding the membrane-distal ligand-binding domain (LBD) of glycoprotein (GP)Ibα induce rapid clearance of platelets and acute thrombocytopenia, which requires the bifurcated antibody structure. It was thought that binding...
Gardado en:
| Publicado en: | J Thromb Haemost |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4755834/ https://ncbi.nlm.nih.gov/pubmed/26662889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.13221 |
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