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The serine protease hepsin mediates urinary secretion and polymerisation of Zona Pellucida domain protein uromodulin
Uromodulin is the most abundant protein in the urine. It is exclusively produced by renal epithelial cells and it plays key roles in kidney function and disease. Uromodulin mainly exerts its function as an extracellular matrix whose assembly depends on a conserved, specific proteolytic cleavage lead...
Zapisane w:
| Wydane w: | eLife |
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| Główni autorzy: | , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
eLife Sciences Publications, Ltd
2015
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4755741/ https://ncbi.nlm.nih.gov/pubmed/26673890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.08887 |
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