Up-Regulation of ENO1 by HIF-1α in Retinal Pigment Epithelial Cells after Hypoxic Challenge Is Not Involved in the Regulation of VEGF Secretion

PURPOSE: Alpha-enolase (ENO1), a major glycolytic enzyme, is reported to be over-expressed in various cancer tissues. It has been demonstrated to be regulated by the Hypoxia-inducible factor 1-α (HIF-1α), a crucial transcriptional factor implicated in tumor progression and cancer angiogenesis. Choro...

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Gepubliceerd in:PLoS One
Hoofdauteurs: Zheng, Feihui, Jang, Wai-Chi, Fung, Frederic K. C., Lo, Amy C. Y., Wong, Ian Y. H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2016
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755565/
https://ncbi.nlm.nih.gov/pubmed/26882120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147961
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