Mps1(Mph1) Kinase Phosphorylates Mad3 to Inhibit Cdc20(Slp1)-APC/C and Maintain Spindle Checkpoint Arrests

The spindle checkpoint is a mitotic surveillance system which ensures equal segregation of sister chromatids. It delays anaphase onset by inhibiting the action of the E3 ubiquitin ligase known as the anaphase promoting complex or cyclosome (APC/C). Mad3/BubR1 is a key component of the mitotic checkp...

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Detaylı Bibliyografya
Yayımlandı:PLoS Genet
Asıl Yazarlar: Zich, Judith, May, Karen, Paraskevopoulos, Konstantinos, Sen, Onur, Syred, Heather M., van der Sar, Sjaak, Patel, Hitesh, Moresco, James J., Sarkeshik, Ali, Yates, John R., Rappsilber, Juri, Hardwick, Kevin G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2016
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755545/
https://ncbi.nlm.nih.gov/pubmed/26882497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005834
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