Enantioselective Synthesis of 3,5,6‐Substituted Dihydropyranones and Dihydropyridinones using Isothiourea‐Mediated Catalysis

The scope of dihydropyranone and dihydropyridinone products accessible by isothiourea‐catalyzed processes has been expanded and explored through the use of 2‐N‐tosyliminoacrylates and 2‐aroylacrylates in a Michael addition‐lactonization/lactamization cascade reaction. Notably, to ensure reproducibil...

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Publicado en:Chem Asian J
Main Authors: Stark, Daniel G., Morrill, Louis C., Cordes, David B., Slawin, Alexandra M. Z., O'Riordan, Timothy J. C., Smith, Andrew D.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755233/
https://ncbi.nlm.nih.gov/pubmed/26471245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/asia.201500907
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