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Leukemia‐associated Rho guanine‐nucleotide exchange factor is not critical for RhoA regulation, yet is important for platelet activation and thrombosis in mice
BACKGROUND: RhoA is an important regulator of platelet responses downstream of Gα(13), yet we still know little about its regulation in platelets. Leukemia‐associated Rho guanine‐nucleotide exchange factor (GEF [LARG]), a RhoA GEF, is highly expressed in platelets and may constitute a major upstream...
Gorde:
| Argitaratua izan da: | J Thromb Haemost |
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| Egile Nagusiak: | , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
John Wiley and Sons Inc.
2015
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4755168/ https://ncbi.nlm.nih.gov/pubmed/26334261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.13129 |
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