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Engineered IgG1‐Fc – one fragment to bind them all
The crystallizable fragment (Fc) of the immunoglobulin class G (IgG) is a very attractive scaffold for the design of novel therapeutics due to its quality of uniting all essential antibody functions. This article reviews the functionalization of this homodimeric glycoprotein by diversification of st...
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| 出版年: | Immunol Rev |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4755133/ https://ncbi.nlm.nih.gov/pubmed/26864108 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12385 |
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