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Engineered IgG1‐Fc – one fragment to bind them all
The crystallizable fragment (Fc) of the immunoglobulin class G (IgG) is a very attractive scaffold for the design of novel therapeutics due to its quality of uniting all essential antibody functions. This article reviews the functionalization of this homodimeric glycoprotein by diversification of st...
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| Publicado no: | Immunol Rev |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4755133/ https://ncbi.nlm.nih.gov/pubmed/26864108 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12385 |
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