The rarity of ALDH (+) cells is the key to separation of normal versus leukemia stem cells by ALDH activity in AML patients

To understand the precise disease driving mechanisms in acute myeloid leukemia (AML), comparison of patient matched hematopoietic stem cells (HSC) and leukemia stem cells (LSC) is essential. In this analysis, we have examined the value of aldehyde dehydrogenase (ALDH) activity in combination with CD...

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Detalhes bibliográficos
Publicado no:Int J Cancer
Main Authors: Hoang, Van T., Buss, Eike C., Wang, Wenwen, Hoffmann, Isabel, Raffel, Simon, Zepeda‐Moreno, Abraham, Baran, Natalia, Wuchter, Patrick, Eckstein, Volker, Trumpp, Andreas, Jauch, Anna, Ho, Anthony D., Lutz, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Cancer Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755039/
https://ncbi.nlm.nih.gov/pubmed/25545165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.29410
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