Loading...

Efficient conversion of primary azides to aldehydes catalyzed by active site variants of myoglobin

The oxidation of primary azides to aldehydes constitutes a convenient but underdeveloped transformation for which no efficient methods are available. Here, we demonstrate that engineered variants of the hemoprotein myoglobin can catalyze this transformation with high efficiency (up to 8500 turnovers...

Full description

Saved in:
Bibliographic Details
Published in:Chem Sci
Main Authors: Giovani, Simone, Singh, Ritesh, Fasan, Rudi
Format: Artigo
Language:Inglês
Published: Royal Society of Chemistry 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4754990/
https://ncbi.nlm.nih.gov/pubmed/26900445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc02857d
Tags: Add Tag
No Tags, Be the first to tag this record!