Knockout of BRD7 results in impaired spermatogenesis and male infertility

BRD7 was originally identified as a novel bromodomain gene and a potential transcriptional factor. BRD7 was found to be extensively expressed in multiple mouse tissues but was highly expressed in the testis. Furthermore, BRD7 was located in germ cells during multiple stages of spermatogenesis, rangi...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Wang, Heran, Zhao, Ran, Guo, Chi, Jiang, Shihe, Yang, Jing, Xu, Yang, Liu, Yukun, Fan, Liqing, Xiong, Wei, Ma, Jian, Peng, Shuping, Zeng, Zhaoyang, Zhou, Yanhong, Li, Xiayu, Li, Zheng, Li, Xiaoling, Schmitt, David C., Tan, Ming, Li, Guiyuan, Zhou, Ming
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4754950/
https://ncbi.nlm.nih.gov/pubmed/26878912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21776
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