Knockout of BRD7 results in impaired spermatogenesis and male infertility

BRD7 was originally identified as a novel bromodomain gene and a potential transcriptional factor. BRD7 was found to be extensively expressed in multiple mouse tissues but was highly expressed in the testis. Furthermore, BRD7 was located in germ cells during multiple stages of spermatogenesis, rangi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wang, Heran, Zhao, Ran, Guo, Chi, Jiang, Shihe, Yang, Jing, Xu, Yang, Liu, Yukun, Fan, Liqing, Xiong, Wei, Ma, Jian, Peng, Shuping, Zeng, Zhaoyang, Zhou, Yanhong, Li, Xiayu, Li, Zheng, Li, Xiaoling, Schmitt, David C., Tan, Ming, Li, Guiyuan, Zhou, Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4754950/
https://ncbi.nlm.nih.gov/pubmed/26878912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21776
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