Knockout of BRD7 results in impaired spermatogenesis and male infertility

BRD7 was originally identified as a novel bromodomain gene and a potential transcriptional factor. BRD7 was found to be extensively expressed in multiple mouse tissues but was highly expressed in the testis. Furthermore, BRD7 was located in germ cells during multiple stages of spermatogenesis, rangi...

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Udgivet i:Sci Rep
Main Authors: Wang, Heran, Zhao, Ran, Guo, Chi, Jiang, Shihe, Yang, Jing, Xu, Yang, Liu, Yukun, Fan, Liqing, Xiong, Wei, Ma, Jian, Peng, Shuping, Zeng, Zhaoyang, Zhou, Yanhong, Li, Xiayu, Li, Zheng, Li, Xiaoling, Schmitt, David C., Tan, Ming, Li, Guiyuan, Zhou, Ming
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4754950/
https://ncbi.nlm.nih.gov/pubmed/26878912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21776
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