Knockout of BRD7 results in impaired spermatogenesis and male infertility

BRD7 was originally identified as a novel bromodomain gene and a potential transcriptional factor. BRD7 was found to be extensively expressed in multiple mouse tissues but was highly expressed in the testis. Furthermore, BRD7 was located in germ cells during multiple stages of spermatogenesis, rangi...

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Publicado en:Sci Rep
Autores principales: Wang, Heran, Zhao, Ran, Guo, Chi, Jiang, Shihe, Yang, Jing, Xu, Yang, Liu, Yukun, Fan, Liqing, Xiong, Wei, Ma, Jian, Peng, Shuping, Zeng, Zhaoyang, Zhou, Yanhong, Li, Xiayu, Li, Zheng, Li, Xiaoling, Schmitt, David C., Tan, Ming, Li, Guiyuan, Zhou, Ming
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4754950/
https://ncbi.nlm.nih.gov/pubmed/26878912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21776
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