Pseudomonas aeruginosa exoenzymes U and Y induce a transmissible endothelial proteinopathy

We tested the hypothesis that Pseudomonas aeruginosa type 3 secretion system effectors exoenzymes Y and U (ExoY and ExoU) induce release of a high-molecular-weight endothelial tau, causing transmissible cell injury characteristic of an infectious proteinopathy. Both the bacterial delivery of ExoY an...

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Publicado en:Am J Physiol Lung Cell Mol Physiol
Main Authors: Morrow, K. Adam, Ochoa, Cristhiaan D., Balczon, Ron, Zhou, Chun, Cauthen, Laura, Alexeyev, Mikhail, Schmalzer, Katherine M., Frank, Dara W., Stevens, Troy
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2015
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4754902/
https://ncbi.nlm.nih.gov/pubmed/26637633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00103.2015
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