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The Pseudomonas aeruginosa exoenzyme Y impairs endothelial cell proliferation and vascular repair following lung injury

Exoenzyme Y (ExoY) is a Pseudomonas aeruginosa toxin that is introduced into host cells through the type 3 secretion system (T3SS). Once inside the host cell cytoplasm, ExoY generates cyclic nucleotides that cause tau phosphorylation and microtubule breakdown. Microtubule breakdown causes interendot...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Stevens, Trevor C., Ochoa, Cristhiaan D., Morrow, K. Adam, Robson, Matthew J., Prasain, Nutan, Zhou, Chun, Alvarez, Diego F., Frank, Dara W., Balczon, Ron, Stevens, Troy
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Physiological Society 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4025060/
https://ncbi.nlm.nih.gov/pubmed/24705722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00135.2013
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