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Identification of a prostaglandin D(2) metabolite as a neuritogenesis enhancer targeting the TRPV1 ion channel

Mast cells play important roles in allergic inflammation by secreting various mediators. In the present study, based on the finding that the medium conditioned by activated RBL-2H3 mast cells enhanced the nerve growth factor (NGF)-induced neuritogenesis of PC12 cells, we attempted to isolate an acti...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Shibata, Takahiro, Takahashi, Katsuhiro, Matsubara, Yui, Inuzuka, Emi, Nakashima, Fumie, Takahashi, Nobuaki, Kozai, Daisuke, Mori, Yasuo, Uchida, Koji
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4754695/
https://ncbi.nlm.nih.gov/pubmed/26879669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21261
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