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Functional and Structural Divergence in Human TRPV1 Channel Subunits by Oxidative Cysteine Modification

Transient receptor potential vanilloid 1 (TRPV1) channel is a tetrameric protein that acts as a sensor for noxious stimuli such as heat and for diverse inflammatory mediators such as oxidative stress to mediate nociception in a subset of sensory neurons. In TRPV1 oxidation sensing, cysteine (Cys) ox...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Ogawa, Nozomi, Kurokawa, Tatsuki, Fujiwara, Kenji, Polat, Onur Kerem, Badr, Heba, Takahashi, Nobuaki, Mori, Yasuo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4759194/
https://ncbi.nlm.nih.gov/pubmed/26702055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.700278
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