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Estimating Effect Sizes and Expected Replication Probabilities from GWAS Summary Statistics
Genome-wide Association Studies (GWAS) result in millions of summary statistics (“z-scores”) for single nucleotide polymorphism (SNP) associations with phenotypes. These rich datasets afford deep insights into the nature and extent of genetic contributions to complex phenotypes such as psychiatric d...
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| Udgivet i: | Front Genet |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4754432/ https://ncbi.nlm.nih.gov/pubmed/26909100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2016.00015 |
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