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New statistical approaches exploit the polygenic architecture of schizophrenia - implications for the underlying neurobiology

Schizophrenia is a complex disorder with high heritability. Recent findings from several large genetic studies suggest a large number of risk variants are involved (i.e., schizophrenia is a polygenic disorder) and analytic approaches could be tailored for this scenario. Novel statistical approaches...

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Bibliografiske detaljer
Udgivet i:Curr Opin Neurobiol
Main Authors: Schork, Andrew J., Wang, Yunpeng, Thompson, Wesley K., Dale, Anders M., Andreassen, Ole A.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380793/
https://ncbi.nlm.nih.gov/pubmed/26555806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.conb.2015.10.008
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