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Reactivation of Aggregated Proteins by the ClpB/DnaK Bi-chaperone System

Protein aggregation is a common problem in protein biochemistry and is linked to many cellular pathologies and human diseases. The molecular chaperone ClpB can resolubilize and reactivate aggregated proteins. This unit describes the procedure for following reactivation of an aggregated enzyme glucos...

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Bibliografiske detaljer
Udgivet i:Curr Protoc Protein Sci
Main Authors: Zolkiewski, Michal, Chesnokova, Liudmila S., Witt, Stephan N.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4753798/
https://ncbi.nlm.nih.gov/pubmed/26836408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/0471140864.ps2810s83
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