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Mechanisms and consequences of ATMIN repression in hypoxic conditions: roles for p53 and HIF-1
Hypoxia-induced replication stress is one of the most physiologically relevant signals known to activate ATM in tumors. Recently, the ATM interactor (ATMIN) was identified as critical for replication stress-induced activation of ATM in response to aphidicolin and hydroxyurea. This suggests an essent...
Zapisane w:
| Wydane w: | Sci Rep |
|---|---|
| Główni autorzy: | , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Nature Publishing Group
2016
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4753685/ https://ncbi.nlm.nih.gov/pubmed/26875667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21698 |
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