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Design, Synthesis, and Immunological Evaluation of Benzyloxyalkyl-Substituted 1,2,3-Triazolyl α-GalCer Analogues
[Image: see text] Replacement of the amide moiety in the structure of α-GalCer with a 1,2,3-triazole linker is known to elicit a response skewed toward Th2 immunity, and glycolipids containing an aromatic ring in the terminus of their acyl or phytosphingosine structural component exhibit an enhanced...
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| Foilsithe in: | ACS Med Chem Lett |
|---|---|
| Main Authors: | , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
American Chemical
Society
2015
|
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4753537/ https://ncbi.nlm.nih.gov/pubmed/26985293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.5b00340 |
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