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Selective potentiation of 2-APB-induced activation of TRPV1–3 channels by acid

Temperature-sensitive TRP channels are important for responses to pain and inflammation, to both of which tissue acidosis is a major contributing factor. However, except for TRPV1, acid-sensing by other ThermoTRP channels remains mysterious. We show here that unique among TRPV1–3 channels, TRPV3 is...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Gao, Luna, Yang, Pu, Qin, Peizhong, Lu, Yungang, Li, Xinxin, Tian, Quan, Li, Yang, Xie, Chang, Tian, Jin-bin, Zhang, Chengwei, Tian, Changlin, Zhu, Michael X., Yao, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4753485/
https://ncbi.nlm.nih.gov/pubmed/26876731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20791
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