A deep sequencing tool for partitioning clearance rates following antimalarial treatment in polyclonal infections

Background and objectives: Current tools struggle to detect drug-resistant malaria parasites when infections contain multiple parasite clones, which is the norm in high transmission settings in Africa. Our aim was to develop and apply an approach for detecting resistance that overcomes the challenge...

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Dades bibliogràfiques
Publicat a:Evol Med Public Health
Autors principals: Mideo, Nicole, Bailey, Jeffrey A., Hathaway, Nicholas J., Ngasala, Billy, Saunders, David L., Lon, Chanthap, Kharabora, Oksana, Jamnik, Andrew, Balasubramanian, Sujata, Björkman, Anders, Mårtensson, Andreas, Meshnick, Steven R., Read, Andrew F., Juliano, Jonathan J.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2016
Matèries:
Original Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4753362/
https://ncbi.nlm.nih.gov/pubmed/26817485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emph/eov036
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