A deep sequencing tool for partitioning clearance rates following antimalarial treatment in polyclonal infections

Background and objectives: Current tools struggle to detect drug-resistant malaria parasites when infections contain multiple parasite clones, which is the norm in high transmission settings in Africa. Our aim was to develop and apply an approach for detecting resistance that overcomes the challenge...

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Detalhes bibliográficos
Publicado no:Evol Med Public Health
Main Authors: Mideo, Nicole, Bailey, Jeffrey A., Hathaway, Nicholas J., Ngasala, Billy, Saunders, David L., Lon, Chanthap, Kharabora, Oksana, Jamnik, Andrew, Balasubramanian, Sujata, Björkman, Anders, Mårtensson, Andreas, Meshnick, Steven R., Read, Andrew F., Juliano, Jonathan J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
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Original Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4753362/
https://ncbi.nlm.nih.gov/pubmed/26817485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emph/eov036
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