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Plasmodium falciparum Drug Resistance Phenotype as Assessed by Patient Antimalarial Drug Levels and Its Association With pfmdr1 Polymorphisms

Background. Multidrug-resistant Plasmodium falciparum is a major threat to global malaria control. Parasites develop resistance by gradually acquiring genetic polymorphisms that decrease drug susceptibility. The aim of this study was to investigate the extent to which parasites with different geneti...

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Detalhes bibliográficos
Main Authors: Malmberg, Maja, Ferreira, Pedro E., Tarning, Joel, Ursing, Johan, Ngasala, Billy, Björkman, Anders, Mårtensson, Andreas, Gil, José P.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563306/
https://ncbi.nlm.nih.gov/pubmed/23225895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jis747
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