Mutations at U2555, a tRNA-protected base in 23S rRNA, affect translational fidelity.
A plasmid carrying a mutation in the highly conserved base U2555 in Escherichia coli 23S rRNA was isolated by selecting for suppression of the -1 frameshift mutation trpE91. U2555 is normally protected in chemical footprinting experiments by the aminoacyl residue of A-site-bound tRNA. Substitution o...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1993
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47533/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8415679/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.19.9214 |
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