Analysis of mutations at residues A2451 and G2447 of 23S rRNA in the peptidyltransferase active site of the 50S ribosomal subunit

On the basis of the recent atomic-resolution x-ray structure of the 50S ribosomal subunit, residues A2451 and G2447 of 23S rRNA were proposed to participate directly in ribosome-catalyzed peptide bond formation. We have examined the peptidyltransferase and protein synthesis activities of ribosomes c...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Thompson, Jill, Kim, Daniel F., O'Connor, Michael, Lieberman, Kate R., Bayfield, Mark A., Gregory, Steven T., Green, Rachel, Noller, Harry F., Dahlberg, Albert E.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2001
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55363/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11470897/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.151257098
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!