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The zebrafish pinball wizard gene encodes WRB, a tail‐anchored‐protein receptor essential for inner‐ear hair cells and retinal photoreceptors
The zebrafish pinball wizard (pwi) mutant is deaf and blind. The pwi phenotype includes a reduced auditory startle response and reduced visual evoked potentials, suggesting fatigue of synaptic release at ribbon synapses in hair cells and photoreceptors. The gene defective in the pwi mutant is WRB, a...
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| Publié dans: | J Physiol |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
John Wiley and Sons Inc.
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4753259/ https://ncbi.nlm.nih.gov/pubmed/26593130 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP271437 |
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