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Uncoupling complement C1s activation from C1q binding in apoptotic cell phagocytosis and immunosuppressive capacity

Complement activation contributes to inflammation in many diseases, yet it also supports physiologic apoptotic cells (AC) clearance and its downstream immunosuppressive effects. The roles of individual complement components in AC phagocytosis have been difficult to dissect with artificially depleted...

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Detalhes bibliográficos
Publicado no:Clin Immunol
Main Authors: Colonna, Lucrezia, Parry, Graham C., Panicker, Sandip, Elkon, Keith B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4753131/
https://ncbi.nlm.nih.gov/pubmed/26769276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2015.12.017
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