IgM-Dependent Phagocytosis in Microglia is Mediated by Complement Receptor 3, not Fcα/μ Receptor

Microglia play an important role in receptor-mediated phagocytosis in the CNS. In brain abscess and other CNS infections, invading bacteria undergo opsonization with immunoglobulins (Ig) or complement. Microglia recognize these opsonized pathogens by Fc or complement receptors triggering phagocytosi...

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Pubblicato in:J Immunol
Autori principali: Weinstein, Jonathan R., Quan, Yi, Hanson, Josiah F., Colonna, Lucrezia, Iorga, Michael, Honda, Shin-ichiro, Shibuya, Kazuko, Shibuya, Akira, Elkon, Keith B., Möller, Thomas
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4655136/
https://ncbi.nlm.nih.gov/pubmed/26500348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401195
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