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Intranasal insulin protects against substantia nigra dopaminergic neuronal loss and alleviates motor deficits induced by 6-OHDA in rats
Protection of substantia nigra (SN) dompaminergic (DA) neurons by neurotrophic factors (NTF) is one of the promising strategies in Parkinson’s disease (PD) therapy. A major clinical challenge for NTF-based therapy is that NTFs need to be delivered into the brain via invasive means, which often shows...
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| Publicado no: | Neuroscience |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4753102/ https://ncbi.nlm.nih.gov/pubmed/26777890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2016.01.020 |
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