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Serine-arginine protein kinase 1 (SRPK1), a determinant of angiogenesis, is upregulated in prostate cancer and correlates with disease stage and invasion

Vascular endothelial growth factor (VEGF) undergoes alternative splicing to produce both proangiogenic and antiangiogenic isoforms. Preferential splicing of proangiogenic VEGF is determined by serine-arginine protein kinase 1 (SRPK1), which is upregulated in a number of cancers. In the present study...

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Библиографические подробности
Опубликовано в: :J Clin Pathol
Главные авторы: Bullock, Nicholas, Potts, Jonathan, Simpkin, Andrew J, Koupparis, Anthony, Harper, Steve J, Oxley, Jon, Oltean, Sebastian
Формат: Artigo
Язык:Inglês
Опубликовано: BMJ Publishing Group 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4752636/
https://ncbi.nlm.nih.gov/pubmed/26500332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jclinpath-2015-203125
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