SERINE ARGININE PROTEIN KINASE-1 (SRPK1) INHIBITION AS A POTENTIAL NOVEL TARGETED THERAPEUTIC STRATEGY IN PROSTATE CANCER

Angiogenesis is required for tumour growth and is induced principally by VEGF-A. VEGF-A pre-mRNA is alternatively spliced at the terminal exon to produce two families of isoforms, pro- and anti-angiogenic, only the former of which is upregulated in prostate cancer. In renal epithelial cells and colo...

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Udgivet i:Oncogene
Main Authors: Mavrou, Athina, Brakspear, Karen, Hamdollah-Zadeh, Maryam, Damodaran, Gopinath, Babaei-Jadidi, Roya, Oxley, Jon, Gillatt, David A, Ladomery, Michael R, Harper, Steven J, Bates, David O, Oltean, Sebastian
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351909/
https://ncbi.nlm.nih.gov/pubmed/25381816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.360
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