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Serine-arginine protein kinase 1 (SRPK1), a determinant of angiogenesis, is upregulated in prostate cancer and correlates with disease stage and invasion

Vascular endothelial growth factor (VEGF) undergoes alternative splicing to produce both proangiogenic and antiangiogenic isoforms. Preferential splicing of proangiogenic VEGF is determined by serine-arginine protein kinase 1 (SRPK1), which is upregulated in a number of cancers. In the present study...

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Pubblicato in:J Clin Pathol
Autori principali: Bullock, Nicholas, Potts, Jonathan, Simpkin, Andrew J, Koupparis, Anthony, Harper, Steve J, Oxley, Jon, Oltean, Sebastian
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4752636/
https://ncbi.nlm.nih.gov/pubmed/26500332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jclinpath-2015-203125
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