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Serine-arginine protein kinase 1 (SRPK1), a determinant of angiogenesis, is upregulated in prostate cancer and correlates with disease stage and invasion

Vascular endothelial growth factor (VEGF) undergoes alternative splicing to produce both proangiogenic and antiangiogenic isoforms. Preferential splicing of proangiogenic VEGF is determined by serine-arginine protein kinase 1 (SRPK1), which is upregulated in a number of cancers. In the present study...

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Detalhes bibliográficos
Publicado no:J Clin Pathol
Main Authors: Bullock, Nicholas, Potts, Jonathan, Simpkin, Andrew J, Koupparis, Anthony, Harper, Steve J, Oxley, Jon, Oltean, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4752636/
https://ncbi.nlm.nih.gov/pubmed/26500332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jclinpath-2015-203125
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