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TRAIL and TRAIL receptors splice variants during long-term interferon β treatment of patients with multiple sclerosis: evaluation as biomarkers for therapeutic response

OBJECTIVE: We aimed to assess the effects of interferon β (IFNβ) treatment on the expression of the splice variants of the Tumour necrosis factor-Related Apoptosis Inducing Ligand (TRAIL) and its receptors in different cell subpopulations (CD14+, CD4+ and CD8+) from patients with multiple sclerosis...

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Detalhes bibliográficos
Publicado no:J Neurol Neurosurg Psychiatry
Main Authors: López-Gómez, Carlos, Oliver-Martos, Begoña, Pinto-Medel, María-Jesús, Suardiaz, Margarita, Reyes-Garrido, Virginia, Urbaneja, Patricia, Fernández, Óscar, Leyva, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4752633/
https://ncbi.nlm.nih.gov/pubmed/25736057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp-2014-309932
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