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Intracochlear Drug Delivery through the Oval Window in Fresh Cadaveric Human Temporal Bones
HYPOTHESIS: Drug delivered to the oval window can diffuse to the apex of the human cochlea. BACKGROUND: We have previously demonstrated that zoledronate, a nitrogen-containing bisphosphonate, can arrest the sensorineural hearing loss in cochlear otosclerosis. We have also shown that, in animals, del...
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| Udgivet i: | Otol Neurotol |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4752383/ https://ncbi.nlm.nih.gov/pubmed/26859540 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MAO.0000000000000964 |
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