Microfabricated Reciprocating Micropump for Intracochlear Drug Delivery with Integrated Drug/Fluid Storage and Electronically Controlled Dosing

The anatomical and pharmacological inaccessibility of the inner ear is a major challenge in drug-based treatment of auditory disorders. This also makes pharmacokinetic characterization of new drugs with systemic delivery challenging, because efficacy is coupled with how efficiently a drug can reach...

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Veröffentlicht in:Lab Chip
Hauptverfasser: Tandon, Vishal, Kang, Woo Seok, Robbins, Tremaan A., Spencer, Abigail J., Kim, Ernest S., McKenna, Michael J., Kujawa, Sharon G., Fiering, Jason, Pararas, Erin E.L., Mescher, Mark J., Sewell, William F., Borenstein, Jeffrey T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766044/
https://ncbi.nlm.nih.gov/pubmed/26778829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5lc01396h
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