Microfabricated Reciprocating Micropump for Intracochlear Drug Delivery with Integrated Drug/Fluid Storage and Electronically Controlled Dosing

The anatomical and pharmacological inaccessibility of the inner ear is a major challenge in drug-based treatment of auditory disorders. This also makes pharmacokinetic characterization of new drugs with systemic delivery challenging, because efficacy is coupled with how efficiently a drug can reach...

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Pubblicato in:Lab Chip
Autori principali: Tandon, Vishal, Kang, Woo Seok, Robbins, Tremaan A., Spencer, Abigail J., Kim, Ernest S., McKenna, Michael J., Kujawa, Sharon G., Fiering, Jason, Pararas, Erin E.L., Mescher, Mark J., Sewell, William F., Borenstein, Jeffrey T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766044/
https://ncbi.nlm.nih.gov/pubmed/26778829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5lc01396h
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